Chris Kresser 8/11/2026

RHR: Why Microglia Are the Key to Brain Health, with Dr. David Perlmutter

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In this episode we discuss: What microglia are and why they’re essential for maintaining healthy brain function How chronic inflammation can transform protective microglia into drivers of neurodegeneration The emerging science of immunometabolism and mitochondrial function Why insulin resistance, obesity, and type 2 diabetes dramatically increase dementia risk The limitations of the traditional am

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RHR: Why Microglia Are the Key to Brain Health, with Dr. David Perlmutter

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