Chris Kresser 2/24/2026

RHR: The Gut-Brain Connection: How Your Microbiome Affects Your Mental Health

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This article/podcast episode examines the link between gut health and mental health, challenging the chemical imbalance theory of depression. It covers the immune-cytokine model, gut inflammation, the role of butyrate, and specific probiotic research (like Bacillus coagulans) for mental health outcomes. It includes functional strategies and references scientific studies.

RHR: The Gut-Brain Connection: How Your Microbiome Affects Your Mental Health

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