Chris Kresser 4/21/2026

RHR: The GLP-1 Blind Spot: What Ozempic Won’t Do for Your Metabolic Health

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In this episode we discuss: How GLP-1 drugs work Proven benefits, common side effects, and discontinuation rates Emerging long-term risks of GLP-1 use The risk of nutrient deficiencies from reduced food intake Muscle loss & body composition changes Weight regain after discontinuing use The lack of root-cause treatments addressing diet, lifestyle, and metabolic drivers Who benefits most from GLP-1s

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RHR: The GLP-1 Blind Spot: What Ozempic Won’t Do for Your Metabolic Health

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